Rapid Lateral Test Principles

In vitro diagnostic test strips based on the principles of immunochromatography exist for a wide array of target analytes. The first tests were made for the detection of human chorionic gonadotropin (hCG). Today, there are commercially available tests for monitoring ovulation, detecting infectious disease organisms, analyzing drugs of abuse, and measuring other analytes important to human physiology. Products have also been introduced for veterinary testing, agricultural applications, environmental testing, and product quality evaluation. While the first tests presented results on the basis of presence/absence, test design has progressed toward semi-quantitative and quantitative assays and the integration of hand-held readers. (See New AT First Technologies)

The Rapid Test Principle
Its test method for the immune chromatography method is the combination of the immunochemistry and the chromatography method, and it is applied with a specific immune reactivity of an antibody to an antigen, coloring characteristic and mobility of a colloidal gold particle, and a molecule’s movement by a capillary phenomenon of a porous membrane.

The immune chromatography method is integrated the specimen dilution in the existing multi-step immune measurement method, cleaning, and the coloring process through the reaction between an enzyme complex and a substrate into one system so that a test can be executed fast and conveniently in one-step. And its test result can be decided without any specific equipment for many advantages of easiness, economic feasibility and fast interpretation of a test result.

Manufacture Technology of Gold Colloid
AT First Diagnostichas itsown technology for Gold colloid assay preparations, which isthe core material use for rapid immunochromatographic assay's. Therefore, we can supply you excellent product stabilities.